Ametrine

Ametrine can be obtained via the following means:
 * Prospecting Titanium Ore
 * Alchemy level 450 - Transmute: Ametrine (Monarch Topaz + Eternal Shadow)
 * Icy Prism and Ashen Sack of Gems has a chance of yielding an epic gem.

Jewelcrafting

 * Champion's Ametrine
 * Deadly Ametrine
 * Deft Ametrine
 * Empowered Ametrine
 * Fierce Ametrine
 * Glimmering Ametrine
 * Inscribed Ametrine
 * Lucent Ametrine
 * Luminous Ametrine
 * Potent Ametrine
 * Pristine Ametrine
 * Reckless Ametrine
 * Resolute Ametrine
 * Resplendent Ametrine
 * Stalwart Ametrine
 * Stark Ametrine
 * Wicked Ametrine
 * Willful Ametrine

Prior to patch 4.0.1 Ametrine was also used for crafting the following:
 * Accurate Dreadstone
 * Etched Dreadstone
 * Glinting Dreadstone
 * Veiled Dreadstone