It is still possible for the Cold Blood-modified attack to be dodged, parried, blocked, or miss; in this situation the Cold Blood buff will not be lost, and will still apply to the next special attack.
Like all "on next attack" abilities, Cold Blood does NOT activate the global cooldown, and can thus be bound to a macro with another ability.
While Cold Blood is active, the Rogue's right hand will have a blue aura emitting snow crystals around it.
Patch 10.0.0 (2022-10-25): Re-added and updated as a row 9 class talent (was a tier 3 Assassination talent). Increases the critical strike chance of your next damaging ability by 100%. Cooldown reduced to 45 sec (was 3 min).
Old: When activated, generates 25 Energy and increases the critical strike chance of your next non-periodic offensive ability by 100%.